Medications for ADHD include various options, from fast-acting stimulants to non-stimulant medications suitable for specific situations. Side effects are generally mild and manageable, and effective therapy can usually be tailored to significantly improve quality of life. There are several main categories of medications for treating ADHD:
Stimulants
This group is considered the most effective for treating ADHD and has been studied for over 60 years in both children and adults. Numerous studies have demonstrated their safety and effectiveness in reducing the symptoms of the disorder. These medications work by increasing levels of neurotransmitters (chemicals that transmit signals between nerve cells) in brain areas related to attention and concentration, which behave differently in individuals with ADHD.
These medications help lessen symptoms like hyperactivity, impulsivity, distractibility, and difficulties with executive functions. The differences among various medications stem from how the active ingredient is released and the drug's composition, which affect the duration of the effect, onset time, and side effects.
Examples of Stimulants
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Methylphenidate: Ritalin (immediate-release or sustained-release), Ritalin LA, Concerta
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Dexmethylphenidate: Focalin, Daytrana (dermal patch)
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Amphetamines: Attent, Vyvanse
Non-Stimulant Medications
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Atomoxetine: A long-lasting medication similar in action to anti-anxiety medications. It may take several weeks for its effects to begin.
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Adrenergic Drugs: Clonidine and guanfacine, which are also used to treat high blood pressure. They are not considered first-line treatments for ADHD but may be effective in certain cases or in combination with stimulants.
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Antidepressants: Such as bupropion, which is recommended for cases of depression in addition to ADHD.
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Other Medications: Such as Effexor, SSRIs (serotonin) or tricyclics, which are recommended when there is a co-occurring disorder or when first-line medications are ineffective.
Side Effects
Side effects are typically reversible and diminish over time. In most cases, the therapy can be adjusted for greater effectiveness and fewer significant side effects.
Common Side Effects
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Loss of Appetite: A common issue, especially at the beginning of treatment, but usually resolves after a few weeks. This can be managed by taking the medication after breakfast and maintaining regular eating habits.
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Difficulty Falling Asleep: May occur due to the medication's effect on alertness. This can be avoided by taking the medication in the morning or switching to a fast-acting formulation.
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Anxiety or Restlessness: May arise in individuals prone to anxiety. This can be managed by adjusting the dosage or switching medications.
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Rebound Symptoms: Increased symptoms such as distractibility, impulsivity, or fatigue after the medication wears off. This side effect can be minimized by adjusting the timing of medication intake or engaging in physical activity.
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Emotional Numbness or Cognitive Rigidity: May occur if the dosage is incorrect. In such cases, the dosage or type of medication should be changed.
Other (Less Common) Side Effects: Fatigue, nausea, dizziness, decreased blood pressure, and other largely reversible and manageable side effects.
Before Starting Medication
The physician will check for other disorders (both physical and psychiatric). Blood tests, blood pressure checks, and ECG evaluations are recommended, along with a review of other medications being taken. It is essential to receive a detailed explanation from the physician about how to take the medication and the medical monitoring at the start of treatment. These components help patients adjust to the medication while preventing side effects and misuse. It is important to ask the doctor when to report any problems or changes experienced, such as appetite loss, changes in eating habits, sleep disturbances, cognitive rigidity, and persistent feelings of apathy or tension. These changes can interfere with treatment but can often be managed by switching medications, modifying lifestyle habits like reducing sleep deprivation, adjusting eating habits, increasing physical activity, or, in some cases, adding an anti-anxiety medication or alternative therapies. For instance, a person experiencing increased tension from medication may benefit from incorporating mindfulness practices to help reduce it.
Apps and Technologies for Medication Monitoring
Forgetfulness, difficulty with persistence, and disorganization are some symptoms of ADHD that can interfere with medication therapy. Apps that help with reminders, time management, and planning can be beneficial. These apps track how the medication affects the individual, what symptoms have improved, and any side effects.
Additionally, specialized apps can help manage side effects related to the disorder, such as sleep disturbances, emotional issues, anxiety, and depression. For example, apps that promote better sleep and eating habits, along with those that encourage relaxation exercises, meditation, and physical activity, can complement medication and improve its chances of success.
Using Neurocognitive Tests and Structured Questionnaires for Medication Monitoring
Awareness of the expected changes in symptoms with medication is crucial for therapeutic success and developing better behavioral and coping strategies. In medical monitoring, it is important to identify the changes that have occurred, which can significantly enhance self-esteem and confidence.
Using structured questionnaires (completed before and during treatment) can be very helpful for measuring and defining changes, as well as understanding the role of medication in these changes.
Computerized neurocognitive tests are valuable for understanding the core difficulties of the disorder, such as attention issues and impaired executive function, but they are not necessary for diagnosis. Conducting these tests before starting medication can sometimes help clarify the disorder and increase awareness of its symptoms. During treatment, if functional improvement is observed, cognitive tests may be repeated while on medication. This process reinforces personal experience while enhancing understanding of the disorder and how to address its components.
Duration of Medication and Discontinuation
The physician will work with the patient to determine when there is a greater or lesser need for medication. Some adults may need medication specifically during work hours or for certain tasks (like office work), while others may require it to enhance interpersonal interactions or function within the family and home. Some individuals may need medication for academic settings or self-management.
Similarly, regarding how long to use medication, changes in a person's daily responsibilities, pressures in different areas of life, and the severity of symptoms require regular evaluation of the benefits of treatment. Some people may need medication for a short time, while others may find it helpful to use it indefinitely.
Recent studies have shown that taking medication under regular medical supervision lowers the risk of illness and death in adults with ADHD compared to the general population.
It's important to note that ultimately, each person, in collaboration with their doctor, will make personal decisions based on what is best for them.